1,1-Cyclobutanedicarboxylatodiammineplatinum (II) Cas:41575-94-4
| Nama Putumōhio | XD90684 |
| Ingoa Hua | 1,1-Cyclobutanedicarboxylatodiammineplatinum (II) |
| CAS | 41575-94-4 |
| Tātai rāpoi | C6H12N2O4Pt |
| Taumaha rāpoi | 371.25 |
| Nga Taipitopito Rokiroki | 2-8°C |
| Waehere Rere Whakariterite | 28439090 |
Whakatakotoranga Hua
| Te ahua | Ma ki te paura ma |
| Te whakamatautau | 99% |
| Wai | ≤0.5% |
| Ngaronga i te whakamaroke | ≤0.5% |
| pūhaumāota | ≤100ppm |
| Nga Taonga Paanga | ≤0.25% |
| Tetahi poke kore i tohua | ≤ 0.1% |
| Ko era atu poke katoa | ≤0.5% |
| 1,1-Cyclobutanedicarboxylic acid | ≤ 0.5% |
Whakatupuranga tuarua konukawata matatini raau taero antineoplastic.He rite te ahua o te tuwha antitumor me te mahi antitumor ki era o te cisplatin, engari he pai ake te wairewa o te wai i to te cisplatin, he iti hoki te paitini ki te whatukuhu.He pai te rongoa i runga i te mate pukupuku o te puku iti, te mate pukupuku ovarian, te mahunga me te kaki squamous cell carcinoma, te puku testicular, lymphoma kino, me etahi atu. Ka taea hoki te whakamahi mo te mate pukupuku pukupuku, te pukupuku pukupuku, etc
Ko nga reanga tuarua o nga raau taero anticancer platinum he rite tonu nga mahi me te whakamahi ki te cisplatin.He kaha ake i te cisplatin mo etahi pukupuku, a he kaha ake i te cisplatin hei radiosensitizer i raro i nga tikanga hypoxic.Ka whakamahia te nuinga mo te mate pukupuku ovarian, te mate pukupuku testicular, te mate pukupuku pūtau iti me te mate pukupuku o te upoko me te kaki.
Ko te Carboplatin he rongoa mo te mate pukupuku e pa ana ki te konukawata e pakaru ana i te DNA ma te hanga i te hononga intrachain ki nga toenga guanine e tata ana.Ko te painga antitumor o enei raau taero ka tutuki ma te ngaro o te mahi whakatikatika DNA (kano kano MMR) me te whakaurunga o te mate pūtau kua whakaritea.
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