Hua

Hei tirotiro i te painga o te whakakotahitanga o te butyrate, Lactobacillus casei, me L-carnitine i roto i te tauira colitis kiore.I wehea nga kiore kia whitu nga roopu.E wha nga roopu i whiwhi i te butyrate waha, L-carnitine, Lactobacillus casei me te whakakotahitanga o nga raau taero e toru mo nga ra 10.Ko nga roopu e toe ana ko nga whakahaere kino me te pai me te roopu horihori.Macroscopic, histopathological examinations, and biomarkers such as tumor necrosis factor-alpha (TNF-α) and interlukin-1β (IL-1β), myeloperoxidase (MPO), thiobarbituric acid reactive substances (TBARS), and ferric reduced ability of plasma (FRAP) ) i whakatauhia i roto i te koroni.I whakaatuhia e te maimoatanga huinga he painga tino painga ki te whakaheke i te colitis i whakaritea ki nga mana whakahaere.Ko nga huringa katoa o te whakahekenga o te TNF-α (114.66 ± 18.26 vs 171.78 ± 9.48 pg / mg pūmua, P <0.05), IL-1β (24.9 ± 1.07 vs 33.06 ± 2.16 pg / mg pūmua, P <0.0.05), TBARS ± 0.03 vs 0.49 ± 0.04 μg/mg pūmua, P <0.01), MPO (15.32 ± 0.4 vs 27.24 ± 3.84 U/mg pūmua, P <0.05), me te teitei o te FRAP (23.46 ± 1.2 μL vs 1.2 μL) , P <0.05) e tautoko ana i te hiahia o te rongoa whakakotahi ki te whakataurite ki nga mana whakahaere.Ahakoa i whai hua ano nga monotherapies ki te whakapai ake i nga tohu colitis, he pai ake te rongoa whakakotahi ki te whakapai ake i nga tohu ahotea oxidative koroni tae atu ki te FRAP, TBARS, me te MPO. te waahi haumanu.