Hua

Ko te waikawa 3-tert-Butoxycarbonylphenylboronic, e mohiotia ana ko Boc-Ph-B(OH)₂, he puhui waro no te karaehe o te waikawa boronic.Kei roto he mowhiti phenyl kua whakakapihia ki te roopu tert-butoxycarbonyl (Boc) me te roopu waikawa boronic (-B(OH)₂).He maha nga whakamahinga o tenei puhui ki te whakahiato waro, ina koa ki te matū rongoa. Ko tetahi whakamahi tuatahi o te waikawa 3-tert-Butoxycarbonylphenylboronic hei roopu tiaki i te whakahiato waro.Ko te roopu Boc ka taea te taapiri atu ki tetahi roopu mahi amine hei tiaki i a ia mai i nga tauhohenga kore i te wa e whakahiatotia ana nga ngota ngota uaua.Ko te roopu whakamarumaru Boc he pumau i raro i nga momo ahuatanga tauhohenga me te ngawari te tango i muri mai ma te whakamahi i nga tikanga waikawa ngawari, ka taea te whakakore i te roopu amine.Ko tenei taonga ka hangaia te waikawa 3-tert-Butoxycarbonylphenylboronic hei reagent nui i roto i te whakahiato o nga peptides, ho'oraa, me nga hua taiao. I tua atu, ko te waikawa 3-tert-Butoxycarbonylphenylboronic e whakamahia ana i roto i nga tauhohenga whakawhiti, penei i te hononga Suzuki-Miyaura.Ka taea e te roopu waikawa boronic te tauhohenga me tetahi momo organometallic, te tikanga he aryl, alkyl boronate ranei, ka puta he here waro-wao.Ka whakamahia nuitia tenei tauhohenga ki te hanga hanganga ngota ngota uaua me te whakauru i nga roopu aril, alkyl ranei ki runga i te ngota ngota.Ko te waikawa 3-tert-Butoxycarbonylphenylboronic, me tana roopu tiaki Boc, ka taea te whiriwhiri i nga tauhohenga honohono i nga waahi motuhake i roto i te ngota ngota, te whakarei ake i te whai kiko me te whai hua.Ko nga waikawa Boronic, tae atu ki nga hua o te waikawa phenylboronic, kua whakaatu i nga momo mahi koiora, penei i te mate pukupuku, te patu huaketo, me nga taonga antifungal.Ko te kaha o te waikawa 3-tert-Butoxycarbonylphenylboronic ki te uru atu ki nga tauhohenga honohono-whakawhitinga ka taea te whakamahi ki te hoahoa me te whakahiato i nga pūhui hou me nga mahi koiora whakarei.Kua tirotirohia e nga kairangahau te whakahiatotanga o te waikawa boronic acid derivatives o te waikawa 3-tert-Butoxycarbonylphenylboronic me te arotake i to raatau kaha rongoa. tauhohenga.Ko tana hanganga matū ahurei me te tauhohenga ka waiho hei reagent utu nui mo te whakahiatotanga o nga ngota ngota uaua, tae atu ki nga peptides me nga rongoa.I tua atu, ko nga tono rongoa pea o te waikawa 3-tert-Butoxycarbonylphenylboronic me ona huanga ka waiho hei puhui whakamere mo te torotoro haere i roto i te matū rongoa.