![3,3′,5,5′-Tetramethyl-[1,1'-biphenyl]-4,4′-diamine Cas:54827-17-7 99% Whakaahua Whakaatu](http://cdn.globalso.com/xdbiochems/54827-17-71.jpg)
3,3′,5,5′-Tetramethyl-[1,1'-biphenyl]-4,4′-diamine Cas:54827-17-7 99%
| Nama Putumōhio | XD90518 |
| Ingoa Hua | 3,3',5,5'-Tetramethyl-[1,1'-biphenyl]-4,4'-diamine |
| CAS | 54827-17-7 |
| Tātai rāpoi | C16H20N2 |
| Taumaha rāpoi | 240.34 |
| Nga Taipitopito Rokiroki | 2 ki te 8 °C |
| Waehere Rere Whakariterite | 29215990 |
Whakatakotoranga Hua
| Te ahua | He ma, he ma ki te hina, he kowhai ranei te paura |
| Te whakamatautau | >99% |
| Ngaronga i te whakamaroke | <2.0% |
| Mo te rangahau anake, kaua ma te tangata | whakamahi rangahau anake, kaua mo te whakamahi tangata |
Ko Ricin toxin (RT) te tuarua o te paitini whakamate e mohiotia ana;kua tohua e te CDC hei kaihoko whiriwhiri.Ko te RT he mea hanga e te tipu pini katoro;tata ki te 50,000 toni o te RT ka mahia ia tau hei hua o te hinu katoro.E rua nga waahanga iti o te RT, he mekameka A ribotoxic (RTA) me te mekameka B here-galactose (RTB).Ka herea e te RT ki nga pūtau whakangote katoa, ka uru ki roto, ka whakakorea e te RTA kotahi nga ribosomes katoa i roto i te pūtau.Ka tukuna hei aerosol, ka tere te pakaru o te huhu me te fibrosis ka mate.Karekau he kano kano kano kua whakaaetia e te Whakahaere Kai me te Taakaro, ka whai hua noa nga maimoatanga i nga haora tuatahi i muri i te rongonga.Kua whakawhanakehia e matou he kano kano kano RTA e rua nga huringa V76M/Y80A (RiVax).Ko te pūmua e whakaatuhia ana i roto i te Escherichia coli me te kore paitini me te immunogenic i roto i nga kiore, rapeti, me te tangata.Ki te werohia nga kiore kua werohia ki te werohia, ki te aerosolized, ki te hoatu waha ranei (gavaged) RT, ka tiakina katoatia.Kua waihangahia e matou he hanga whakamaoritanga, konumohe-adjuvant-kei roto o RiVax, ka whakamatauria i roto i te rhesus macaques.I muri i nga werohanga e toru, ka whakawhanakehia e nga kararehe nga paturopi hei tiaki i a raatau mai i te horopeta whakamate o te RT aerosolized.Ko enei paturopi i whakakore i te RT me te whakataetae ki nga taumata rereke me te roopu o nga paturopi monoclonal kiore kiore e mohio ana ki te mohio ki nga epitopes motuhake i runga i te RTA taketake.Ko te hua o te whakaaturanga whakataetae antibody ka tohu i te waitohu immunologic mo te whakamarumaru.Ko te mea nui, ko taua hainatanga ano i kitea ma te whakamahi i te sera mai i nga tangata kua werohia e RiVax.
