Albendazole Cas: 54965-21-8
| Nama Putumōhio | XD91873 |
| Ingoa Hua | Albendazole |
| CAS | 54965-21-8 |
| Papanga Molecularla | C12H15N3O2S |
| Taumaha rāpoi | 265.33 |
| Nga Taipitopito Rokiroki | 2-8°C |
| Waehere Rere Whakariterite | 29332990 |
Whakatakotoranga Hua
| Te ahua | Te paura tioata ma |
| Ahahay | 99% min |
| Te rewa | 208-210 °C |
| kiato | 1.2561 (whakatau tata) |
| taupū huritao | 1.6740 (whakatau tata) |
| whakarewatanga | Kare e rewa i roto i te wai, ka whakarewa noa i roto i te waikawa formic anhydrous, he paku noa te wairewa ki te methylene chloride, tata korere ki te waiwaro (96 paiheneti). |
| pka | 10.72±0.10(Te Matapae) |
| Wairewa wai | 0.75mg/L(209 ºC) |
Ko te Albendazole he rongoa hei rongoa i nga mate na te pirinoa.Ka taea te hoatu ki te rongoa i te mate roro onge (neurocysticercosis) ka taea ranei te hoatu hei rongoa i te mate pirinoa e puta ai te mate korere nui (microsporidiosis).
He pärönaki mai i te benzimidazole, ko te albendazole he rongoa me te whanui antihelmintic spectrum.Ka whakaatuhia he paanga antihelmintic ki nga cestodes tairongo me nga nematodes na roto i te aukati i te tukanga o te tangohanga o te glucose e nga parapara, e whakaatuhia ana i roto i te whakahekenga o nga rahui glycogen me te heke o muri mai i te taumata o te adenosintriphophate.Ko te mutunga, ka mutu te neke haere o te parapara ka mate.Ka whakamahia mo te mate o Acaris lumbricoides, Ancylostoma duodenale, Necator americanus, Enterobius vermicularis, me Trichuris trichiura.Ko nga kupu taurite o tenei tarukino ko SKF 62979 me etahi atu.
Ko te Methyl 5-(propylthio)-2-benzimidazolecarbamate (Eskazole,Zentel) he anthelmintic whanui whanui kaore i te maakete i Amerika Te Tai Tokerau.Kei te waatea mai i te kaiwhakanao i runga i te kaupapa aroha.Ka whakamahia nuitia a Albendazole puta noa i te ao mo te maimoatanga o te mate intestinalnematode.He whai hua hei maimoatanga kotahi-horopeta mo te ascariasis, nga mate hookworm o te Ao Hou me te Ao Tawhito, me te trichuriasis.Te whakamaaramatanga maha me te albendazole caneradicate pinworm, threadworm, capillariasis, clonorchiasis, me te mate hydatid.Ko te whai huatanga o te albendazole ki te patu i nga noke (cestodes) he rerekee ake, he iti ake te ahua.
Ka puta te Albendazole hei paura tioata ma e tata kore e rewa ki te wai.Ko te horonga a-waha o albendazole ka whakanuia e te kai momona.Ko te rongoa ka tere me te nui o te whakawhiti tuatahi ki te sulfoxide, ko te ahua kaha i roto i te plasma.Ko te haurua o te ora o te sulfoxide mai i te 10 ki te 15 haora.He nui te whakaputanga biliary me te hangarua enterohepatic o albendazolesulfoxide ka puta.Ko te Albendazole te nuinga o te wa e pai ana ki te rongoa mo te nematodes whekau.Ko te horopeta teitei, te rongoa roa e hiahiatia ana mo te rongoa mate o te clonorchiasis orechinococcal ka puta he paanga kino penei i te paheketanga o te hinu wheua, te pikinga o nga enzyme ate, me te alopecia.
He maha nga mahi a Albendazole ki nga nematodes intestinal me nga cestodes, tae atu ki nga rewharewha ate Opisthorchis sinensis, Opisthorchis viverrini, me Clonorchis sinensis.He pai te whakamahi ki a Giardia lamblia.Ko te Albendazole he rongoa whai hua mo te mate hydatid cyst (echinococcosis), ina koa ka whai tahi me te praziquantel.He pai hoki ki te rongoa i te neurocysticercosis cerebral me te spinal, ina koa ka hoatu me te dexamethasone. E taunaki ana a Albendazole mo te maimoatanga o te gnathostomiasis.
