D-Glutamic acid CAS:6893-26-1 99% Te paura ma
Nama Putumōhio | XD90313 |
Ingoa Hua | D-Glutamic waikawa |
CAS | 6893-26-1 |
Tātai rāpoi | C5H9NO4 |
Taumaha rāpoi | 147.13 |
Nga Taipitopito Rokiroki | Ambient |
Waehere Rere Whakariterite | 29224200 |
Whakatakotoranga Hua
Te ahua | Te paura tioata ma |
Te whakamatautau | 99% |
Te hurihanga motuhake | -31 ki -32.2 |
Nga konganuku taumaha | <10ppm |
AS | <1ppm |
pH | 3 - 3.5 |
SO4 | <0.020% |
Fe | <10ppm |
Ngaronga i te whakamaroke | <0.20% |
Te toenga i runga i te mura | <0.10% |
NH4 | <0.02% |
Cl | <0.02% |
State of Solution | >98% |
Ko nga γ-Glutamyltranspeptidases (γ-GTs) ka wehe i te here γ-glutamyl amide o te glutathione me te whakawhiti i te roopu γ-glutamyl i tukuna ki te wai (hydrolysis) ranei te waikawa amino acceptor (transpeptidation).He mahi nui enei enzyme ki nga waahi katoa i roto i te koiora me te whakahekenga o te glutathione, me te whakakorenga o te xenobiotic.I konei ka ripoatahia e matou te hanganga karaihe taumira 3Å o Bacillus licheniformis γ-GT (BlGT) me tona matatini me te l-Glu.Ko nga hanganga hihi-X e whakau ana ko te BlGT no roto i te N-terminal nucleophilic hydrolase superfamily me te whakaatu kei te pūmua he kowhatu waahi kaha e tuwhera ana he rite ki te korero mo te enzyme homologous mai i Bacillus subtilis, engari he rereke mai i nga mea i kitea mo te γ-GT tangata me mo nga γ-GT mai i etahi atu microorganisms.Ko nga raraunga e kii ana ko te herenga o te l-Glu e whakaohooho ana i te hiku C-terminal o BlGT waahanga nui me te tuku i te tautuhi i te huinga o nga toenga waikawa ka uru pea ki te mohiotanga o te katote whakarewa.Ko te mahi o enei toenga i runga i te whakapumautanga o te BlGT kua rangahaua ma te tohu i te tukatuka aunoa, te mahi enzymatic, te matū me te waiariki denaturation o nga mutants Ala hou e wha.Ko nga hua e whakaatu ana ko te whakakapi i te Asp568 me te Ala ka pa ki te tukatuka aunoa me te pumau o te hanganga o te pūmua.