Furazolidone Cas: 67-45-8
| Nama Putumōhio | XD91885 |
| Ingoa Hua | Furazolidone |
| CAS | 67-45-8 |
| Papanga Molecularla | C8H7N3O5 |
| Taumaha rāpoi | 225.16 |
| Nga Taipitopito Rokiroki | Ambient |
| Waehere Rere Whakariterite | 29349990 |
Whakatakotoranga Hua
| Te ahua | paura kōwhai |
| Ahahay | 99% min |
| Te rewa | 254-256°C (tikura) |
| Kohuatanga | 366.66°C (whakatau tata) |
| kiato | 1.5406 (whakatau tata) |
| taupū huritao | 1.7180 (whakatau tata) |
| Fp | 2 °C |
| whakarewatanga | waikawa formic: wairewa50mg/mL |
| pka | -1.98±0.20(I Matapaetia) |
| Tairongo | Maamaa Maamaa |
| λmax | 365nm(DMSO)(marama) |
| Te pumau | Eu ana.Ka mura.He hotokore ki te kaha o te waiora. |
He rite tonu te awhi antibacterial o te furazolidone ki tera o te furazolidone.Hei rongoa aukati i te mate, he pai ki te rongoa i a Salmonella, Shigella, Escherichia coli, Proteus, Streptococcus, me Staphylococcus aureus.Ehara i te mea ngawari nga huakita ki te whakawhanake i te aukati tarukino tenei tarukino.Karekau hoki he parenga-whakawhiti ki nga paturopi o te karaehe sulfa.Ka whakamahia te nuinga mo te maimoatanga haumanu o te mate koriri, enteritis, typhoid, paratyphoid me te maimoatanga kaupapa o te trichomoniasis tara.
2. Ko te hua he fungicide he whanui antibacterial spectrum.Hei rongoa aukati, he pai mo te rongoa i nga momo huakita Gram-pai me te kino tae atu ki te Escherichia coli, Bacillus anthracis, me te paratyphoid bacilli.Ehara i te mea whai hua anake mo te mate koriri, enteritis, engari ka whakamahia ano mo te rongoa i nga mate tara.I nga tau tata nei, he pai te whai hua mo te maimoatanga o te mate taipoid.Hei taapiri mo nga raau taero kararehe me te inu, he paanga antibacterial ahurei i runga i te Salmonella, Escherichia coli me Salmonella pullorum me te whai ano hoki i etahi paanga aukati i runga i te protozoa (huakita coccidia, me etahi atu) me te iti ake o te kaha ki te whanake i te aukati tarukino.He iti te furazolidone kua whakamahia mo etahi atu whakamahinga (penei i te peita wairewa-wai me te penupenu pepa) hei patu patu.
3. He rongoa whakaahuru e whakamahia ana hei aukati i te mate o te whekau.
4. Ko te furazolidone, he mea patu patu patu, he whanui antibacterial spectrum.Ko nga huakita tino whakaraerae ko Escherichia coli, Bacillus anthracis, paratyphoid rod, Shigella, me Klebsiella pneumoniae.Ko te Salmonella typhi ano hoki he tairongo ki a ia.Ko te nuinga o te waa e whakamahia ana mo te rongoa i te mate koriri, te enteritis, me te cholera.Ka taea hoki te whakamahi mo te mate taipoi, paratyphoid, giardiasis, me te trichomoniasis.Ko te whakakotahitanga me nga raau taero anti-waikawa ka taea te whakamahi mo te rongoa i te mumura o te kopu na te Helicobacter pylori.Nga ahuatanga: te paura kowhai, te paura tioata ranei, kaore he kakara, i te tuatahi karekau, katahi ka paku kawa;he iti te wairewa ki te wai me te waihano;he iti te wairewa i roto i te chloroform me te kore e rewa i roto i te etera, te whakarewa i te dimethylformamide me te nitromethane.Mp: 255 ki te 259 °C.Tihore i te wa e rewa ana.
Ka whakamahia te Furazolidone i roto i nga mate gastrointestinal me te vaginitis.Ka whakamahia te nuinga i roto i nga whenua whakawhanake ki te rongoa i nga mate diarrhea o nga momo takenga rereke, engari ehara i te mea ko te rongoa pai mena kua tohua he tukumate motuhake.Ko te whakamahi hei kaihoko raina tuarua mo te giardiasis me te waahanga o nga tikanga rongoa maha mo te mate Helicobacter kua tohua.
3-[(5-Nitrofurylidene)amino]-2-oxazolidinone (Furoxone) ka puta hei paura tioata kowhai me te reka kawa i muri.Kare e rewa i te wai, i te waipiro ranei.He mahi huakita a Furazolidone ki te whānuitanga o nga momo mate intestinal, tae atu ki te S. aureus, E. coli, Salmonella, Shigella, Proteus spp., Enterobacter, me Vibrio cholerae. He kaha hoki ki te protozoan Giardia lamblia.E taunakihia ana mo te maimoatanga waha o te huakita, protozoaldiarrhea ranei na nga rauropi whakaraerae.Ko te horopeta o te pakeke ko te 100 mg 4 nga wa ia ra.
He hautanga iti noa iho o te horopeta a-waha o te furazolidoneis ka uru.Tata ki te 5% o te horopeta a-waha ka kitea i roto i te mimi i te ahua o te maha o nga metabolites. Kua puta mai etahi mamae o te gastrointestinal me tana whakamahi. Me karohia te waipiro ina whakamahia te furazolidone na te mea ka taea e te tarukino te aukati i te aldehyde dehydrogenase.
