Iodonitrotetrazolium chloride CAS:146-68-9
| Nama Putumōhio | XD90473 |
| Ingoa Hua | Iodonitrotetrazolium pūhaumāota |
| CAS | 146-68-9 |
| Tātai rāpoi | C19H13ClIN5O2 |
| Taumaha rāpoi | 505.70 |
| Nga Taipitopito Rokiroki | 2 ki te 8 °C |
| Waehere Rere Whakariterite | 32129000 |
Whakatakotoranga Hua
| Tautuhinga | H-NMR |
| Te ahua | Kowhai marama ki te paura karaka |
| Te whakamatautau | >99% |
| Wairewa | He otinga maamaa |
Interferon-induced transmembrane protein 1 (IFITM1) Ko tetahi o nga mema o te whanau o te whanau transmembrane interferon-induced.I roto i tenei rangahau, i kii matou ko te whakahuatanga teitei o te IFITM1 i roto i te mate pukupuku colorectal tangata (CRC) i tino hono ki te CRC lymph node me te metastasis tawhiti tae atu ki te waahanga haumanu matatau ake.Ko te mea nui, ko te whakahuatanga teitei o te IFITM1 he tohu tohu motuhake mo te oranga kore.Hei tirotiro i nga tikanga ngota, i whakaatuhia e matou ko te nui o te whakahuatanga o te IFITM1 i roto i nga ruma CRC i whakatairangahia, engari ko te paheketanga o te whakaaturanga IFITM1 i aukati, te heke / whakaekenga pūtau me te tumorigenicity in vitro.I tua atu, i tautuhia e matou ko Caveolin-1 (CAV1) he kaupapa whakararo o te whakaekenga o te IFITM1-whakauruhia o te pūtau, i te mea ko te paheketanga o te CAV1 i whakakorehia te siIFITM1 i whakakorehia te aukati i te whakaekenga o te pūtau i roto i nga pūtau CRC.I tua atu, i roto i te roopu CRC o nga turorotanga 229, ko te korero o te IFITM1 he rereke ki te korero o te CAV1.Ko enei hua e kii ana ko te IFITM1 e whakatairanga ana i te kaha o nga pūtau CRC, a he tohu tohu tohu pea me te whaainga rongoa mo te CRC.
