L-Alanine CAS: 56-41-7 99% White crystalline paura
Nama Putumōhio | XD90326 |
Ingoa Hua | D-Alanine |
CAS | 338-69-2 |
Tātai rāpoi | C3H7NO2 |
Taumaha rāpoi | 89.09 |
Nga Taipitopito Rokiroki | Ambient |
Waehere Rere Whakariterite | 29224985 |
Whakatakotoranga Hua
Te ahua | Te paura tioata ma |
Te whakamatautau | 98.5 - 101.5% |
Te hurihanga motuhake | +13.7 ki te +15.1 |
Nga konganuku taumaha | <0.0015% |
pH | 5.5 - 7 |
SO4 | <0.03% |
Ngaronga i te whakamaroke | <0.2% |
Te rino | <0.003% |
Te toenga i runga i te mura | <0.15% |
Rahi Matūriki | 200um |
Cl | <0.05% |
Te taumata o nga parahanga pararopi mau tonu | Karekau he poke |
Ko nga γ-Glutamyltranspeptidases (γ-GTs) ka wehe i te here γ-glutamyl amide o te glutathione me te whakawhiti i te roopu γ-glutamyl i tukuna ki te wai (hydrolysis) ranei te waikawa amino acceptor (transpeptidation).He mahi nui enei enzyme ki nga waahi katoa i roto i te koiora me te whakahekenga o te glutathione, me te whakakorenga o te xenobiotic.I konei ka ripoatahia e matou te hanganga karaihe taumira 3Å o Bacillus licheniformis γ-GT (BlGT) me tona matatini me te l-Glu.Ko nga hanganga hihi-X e whakau ana ko te BlGT no roto i te N-terminal nucleophilic hydrolase superfamily me te whakaatu kei te pūmua he kowhatu waahi kaha e tuwhera ana he rite ki te korero mo te enzyme homologous mai i Bacillus subtilis, engari he rereke mai i nga mea i kitea mo te γ-GT tangata me mo nga γ-GT mai i etahi atu microorganisms.Ko nga raraunga e kii ana ko te herenga o te l-Glu e whakaohooho ana i te hiku C-terminal o BlGT waahanga nui me te tuku i te tautuhi i te huinga o nga toenga waikawa ka uru pea ki te mohiotanga o te katote whakarewa.Ko te mahi o enei toenga i runga i te whakapumautanga o te BlGT kua rangahaua ma te tohu i te tukatuka aunoa, te mahi enzymatic, te matū me te waiariki denaturation o nga mutants Ala hou e wha.Ko nga hua e whakaatu ana ko te whakakapi i te Asp568 me te Ala ka pa ki te tukatuka aunoa me te pumau o te hanganga o te pūmua.