L-Tryptophan Cas: 73-22-3 99% White paura
| Nama Putumōhio | XD90295 |
| Ingoa Hua | L-Tryptophan |
| CAS | 73-22-3 |
| Tātai rāpoi | C11H12N2O2 |
| Taumaha rāpoi | 204.22518 |
| Nga Taipitopito Rokiroki | Ambient |
| Waehere Rere Whakariterite | 29339980 |
Whakatakotoranga Hua
| Te whakamatautau | 99% min |
| Te ahua | Te paura ma |
| Kōeke | USP32 |
| Te hurihanga motuhake | -29.4 ki -32.8 |
| pH | 5.5 ki te 7.0 |
| Fe | <0.003% |
| Pb | <0.0015% |
| Ngaronga i te whakamaroke | <0.3% |
| Te toenga i runga i te mura | 0.1%max |
| Cl | 0.05% mōrahi |
Ko te Indoleamine 2,3-dioxygenase (IDO1) me te tryptophan 2,3-dioxygenase (TDO) e rua nga enzyme rereke rereke he rereke te tohatoha o te kiko me nga mahi ahupūngao, engari e rua te huri i te tryptophan ki te N-formylkynurenine (NFK).Ko te IDO1 kua whakamanahia e te haumanu hei whainga raau taero iti mo te mate pukupuku, i te mea ko nga rangahau a-mua e tohu ana ko TDO pea te whaainga mo te mate pukupuku mate pukupuku me te mate neurodegenerative.Kua whakawhanakehia e matou he whakamatautau tirotiro mo te IDO1 me te TDO i runga i te rangahau matū hou, NFK Green, e tauhohe ana me te NFK ki te hanga i tetahi ngota ngota kaakaariki me te roangaru whakahihiri o te 400 nm me te roangaru tuku o te 510 nm.Ka whakaratohia e matou te whakataurite tuatahi o te taha ki te taha o te maha o nga kaitautoko kua whakaputaina o IDO1 me te TDO me te whakaatu ko te Tuhinga o mua o te IDO1 inhibitor Compound 5l e whakaatu ana i te whakawhitinga whakawhitinga nui me te TDO, i te mea kua whakapumautia te whiriwhiringa o etahi atu kaitautoko kua whakaputaina.Ko te pai mo te whakamaaramatanga teitei o nga whakamatautau i whakaatuhia ma te tirotiro i te whare pukapuka o te 87,000 matū matū i roto i te whakatakotoranga 384-, 1536-poka ranei.Ka mutu, ka whakaatu maatau ka taea hoki te whakamahi i te whakamatautau ki te ine i te kaha o nga pūtau ki te whakakoi i te tryptophan me te ine i te kaha o te pūtau o te IDO1 me te aukati TDO.
