Rapamycin mai i Streptomyces hygroscopicus CAS:53123-88-9 Ma ki te ma-ma-ma ranei te paura tioata kowhai
Nama Putumōhio | XD90356 |
Ingoa Hua | Rapamycin mai i Streptomyces hygroscopicus |
CAS | 53123-88-9 |
Tātai rāpoi | C51H79NO13 |
Taumaha rāpoi | 914.17 |
Nga Taipitopito Rokiroki | -20 °C |
Waehere Rere Whakariterite | 2942000000 |
Whakatakotoranga Hua
Te whakamatautau | 99% |
Te ahua | He ma ki te ma-ma, he kowhai ranei te paura tioata |
Ko te Rapamycin, he rongoa kua whakaatuhia ki te whakanui ake i te oranga o nga kiore, ka aukati i te whaainga o te ara rapamycin (TOR), he huarahi nui e whakahaere ana i te tipu o te pūtau me te mana o te kaha.Kua whakapaehia ko te rapamycin me te aukati kai (DR) ka roa te roa o te ora ma nga momo tikanga/ara.Ma te whakamahi i te tātaritanga microarray, ka whakatauritehia e matou te tuhinga o te kiko adipose ma mai i nga kiore whangai rapamycin ranei DR-kai mo te 6 marama.Ko te whakahiatotanga maha me te whakamaarama whakamaarama i whakaatu ko te rapamycin kaore he paanga ki te tuhinga i whakaritea ki a DR.Hei tauira, e ono noa nga tuhinga i whakarerekehia e te rapamycin i te wa e whakaatu ana nga kiore whangai DR he huringa nui i runga i nga tuhinga 1000.Ma te whakamahi i te tātari huarahi mohio, i kitea e DR te huringa o te koiora stearate me te tohu manawataki circadian.Ko o maatau kitenga e whakaatu ana ko te DR, engari ehara i te rapamycin, he paanga ki te transcriptome o te kiko adipose, e kii ana ko enei mahinga e rua ka piki ake te roa o te oranga i roto i nga tikanga rereke / ara.