Tazobactam Cas: 89786-04-9
| Nama Putumōhio | XD92373 |
| Ingoa Hua | Tazobactam |
| CAS | 89786-04-9 |
| Papanga Molecularla | C10H12N4O5S |
| Taumaha rāpoi | 300.29 |
| Nga Taipitopito Rokiroki | -15 ki te -20 °C |
| Waehere Rere Whakariterite | 29419000 |
Whakatakotoranga Hua
| Te ahua | Ma ki te paura ma |
| Ahahay | 99% min |
| Wai | <0.5% |
| Te hurihanga motuhake | +127 ki +139 |
| Nga konganuku taumaha | <20ppm |
| Te toenga i runga i te mura | <0.1% |
| Nga poke katoa | <1.0% |
Ko te Tazobactam he sulfone waikawa penicillanic he rite te hanganga ki te sulbactam.He kaha ake te β-lactamaseinhibitor i te sulbactam, a, he ahua whanui ake te mahi a te waikawa clavulanic.He tino ngoikore te antibacterialactivity.Kei te waatea te Tazobactam i roto i te horopeta-whakarite, nga whakakotahitanga injectable me te piperacillin, he penicillin whanui-a-whanui kei roto i te 8: 1 ōwehenga o te konutai piperacillin ki te tazobactamsodium i te taumaha me te hokohoko i raro i te ingoa hokohoko Zosyn. He tino rite nga pharmacokinetics o nga raau taero e rua.He poto te haurua o te ora e rua (t1/2 ～1 haora), he iti rawa te herenga ki te pūmua, he iti noa iho te paopaotanga, ka pehia ki roto i te mimi i roto i te mimi.
Ko nga tohu kua whakaaetia mo te whakakotahitanga o te piperacillin-tazobactam ko te maimoatanga o te appendicitis, postpartumendometritis, me te pelvic inflammatory disease na te β-lactamase-producing E. coli me Bacteroides spp., te kiri me te hanganga kiri mate na te β-lactamase-producingS.aureus, me te pneumonia na te β-lactamase-producingstrains o H. influenzae.
