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2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-kotahi Cas:1044871-04-6 Whakaahua Whakaatu
  • 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-kotahi Cas:1044871-04-6

2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-kotahi Cas:1044871-04-6

Whakaahuatanga Poto:

Nama Putumōhio: XD90961
Cas: 1044871-04-6
Tātai rāpoi: C24H29N3O4
Taumaha rāpoi: 423.5
Wāteatanga: Kei roto i nga taonga
Utu:  
Pīkī mua:  
Mōkihi Nui: Tono Tono

 


Taipitopito Hua

Tohu Hua

Nama Putumōhio XD90961
Ingoa Hua 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one

CAS

 1044871-04-6

Tātai rāpoi

 C24H29N3O4

Taumaha rāpoi

 423.5
Nga Taipitopito Rokiroki  
Waehere Rere Whakariterite  

 

Whakatakotoranga Hua

Te ahua  
Te whakamatautau  
Bwāhi hinuhinu 612.6±65.0 °C(Te Matapae)
Kiato 1.25±0.1 g/cm3(Te Matapae)
Te whakarea kawa (pKa)9.54±0.20(Te Matapae)

 

Ko te RVX-297 he tino kaha, he aukati BET-waha kua tohua mo te BD2.Ko nga IC50 o RVX-297 mo BRD2 (BD2), BRD3 (BD2), me BRD4 (BD2) ko 0.08, 0.05, me te 0.02 μM.Ka aukati te RVX-297 i te whakaputanga o nga momo ira mumura o nga pūtau aukati.Te kaha o te RVX-297 i roto i nga tauira preclinical o te mumura whakapeka me te autoimmunity.

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    2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-kotahi Cas:1044871-04-6

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