Hua

(4R-Cis)-1,1-Dimethylethyl-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol -1-yl]ethyl] -2,2-dimethyl-1,3-dioxane-4-acetate he pūhui me te hanganga matū matatini.Ahakoa he iti noa nga korero mo nga whakamahinga o tenei puhui, ka taea e tatou te korero mo ona tono pea i runga i ona ahuatanga hanganga me nga ahuatanga noa o nga puhui rite. hei kaihoko whakarewa.Ko te Dioxane he whakarewa noa, ina koa i roto i te matū waro, i te mea he whakarakei ki te wai, he pai hoki te whakarewatanga mo te whānuitanga o nga ngota rauropi.Ko te noho o te wahanga dioxane i roto i tenei puhui e tohu ana tera pea he rite nga ahuatanga memehatanga. I tua atu, ko nga waahanga hanganga o tenei puhui, penei i te roopu warowaiwai fluorophenyl me te phenylamino, e whakaatu ana he mahi koiora pea.Ko te whakakapi i te Fluorine i roto i nga puhui waro ka taea te whakarei ake i o raatau taonga rongoa, ka piki ake pea te kaha, te waatea ranei.Ko te noho mai o te roopu waro phenylamino ka tohu pea i te kaha o te taunekeneke me nga whaainga koiora, tera pea ka arahi ki nga hua whakaora. I runga i enei ahuatanga hanganga, ka taea pea te whakamahi i tenei puhui ki te matū rongoa, ki te whanaketanga tarukino ranei.Ka taea te tirotirohia hei puhui arataki mo te whanaketanga o nga rongoa hou e aro ana ki nga mate motuhake.Heoi, he mea nui kia mohiohia he rangahau ano hei whakatau i ona ahuatanga rongoa, tae atu ki te whaihuatanga, te tikanga o te mahi, me nga paanga taha pea. hei waahanga ranei o te whakahiato matū.Kua whakatewhatewhahia nga paheketanga o te nitronyl me te pyrrole mo te kaha o te whakamahi hei kaikawe waro, hei whakakorikori, hei paraka hanga ranei mo nga hanganga uaua ake.Heoi ano, me whakatewhatewha atu ano enei tono me te arotautanga o nga tikanga whakahiatotanga. I te nuinga, ko te pūhui (4R-Cis) -1,1-Dimethylethyl-6-[2-[2-(4-fluorophenyl)-5-(1- methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate e whakaatu ana i te kaha mo nga tono i roto i te matū rongoa, pūtaiao rauemi, te whakahiato matū ranei.Heoi, he mea nui ki te whakahaere rangahau nui ki te arotake i ona rawa, ki te whakawhanake i nga huarahi whakahiato tika, me te whakatau i ona tono motuhake mo ia mara.