Hua

Ko te momi, te mate huka momo 2 me te hyperlipidemia he maha nga wa ka noho tahi, ka pa atu ki te nui o te mate me te mate.Ko te kai o te warowaiha para me te fructose kua tino piki ake i roto i nga tau tata nei, kua rite ki te pikinga o te mate momona me te mate huka.Kua whakaatuhia e nga rangahau a te tangata me te kararehe ko te nui o te kai hukahuka e pa ana ki te piki haere o te dyslipidemia, te aukati insulin, me te whakaheke toto.Ko te whakangaonga o te fructose ka puta i roto i te ate me te rere o te fructose nui e arai ana ki te whakaemi ake i te whakaemi triglyceride ate (hepatic steatosis).Ko tenei ka paheke te huka me te lipid metabolism me te whakanui ake i te whakaaturanga cytokine proinflammatory.I konei ka whakaatuhia e te fructose te whakarereke i te ahua o te acetyl CoA carboxylase (ACC), te pSer hormone sensitive lipase (pSerHSL) me te adipose triglyceride lipase (ATGL) i roto i te HepG2 hepatic hepatic hepatic cell culture in vitro ranei.I hono tenei ki te pikinga o te de novo triglyceride synthesis in vitro me te hepatic steatosis in vivo i roto i te fructose- versus glucose-whangai me nga kiore whangai kai paerewa.Ko enei rangahau he maarama hou ki nga tikanga e pa ana ki te hypertriglyceridemia ate-a-fructose-mediated hepatic hypertriglyceridemia me te tautuhi i te tango hukahuka hei kaupapa rongoa hou mo nga mate e pa ana ki te lipid.