Hua

Ko te taunekeneke i waenga i te tarukino antidiabetic, Metformin me te kuao kau thymus DNA (CT-DNA) i roto i te (50mM Tris-HCl) parepare i akohia e te UV-Visible absorption, fluorescence, CD spectroscopy and viscosity measurements.I roto i nga rangahau fluorimetric, ko te enthalpy me te entropy o te tauhohenga i waenga i te tarukino me te CT-DNA i whakaatu ko te tauhohenga he exothermic (ΔH=-35.4522 kJ mol(-1); ΔS=-49.9523 J mol(-1)K(-1 )).Ko nga rangahau here whakataetae i whakaatu ka taea e te tarukino te tuku katoa a Hoechst 33258.I whakaatuhia e te matatini te hyperchromism absorption i roto i tana hihinga UV-Vis me te DNA.Ko te taumau herenga tatau, K(b), i riro mai i nga rangahau whakaurunga UV-Vis he 8.3×10(4)M(-1).I tua atu, ko nga huringa o te CD spectra i te aroaro o te tarukino e whakaatu ana i te whakapumautanga o te ahua B ringa matau o CT-DNA.Ka mutu, ka kitea e te inenga pokey ko te herenga o te matatini ki te CT-DNA ka herea te mata, te nuinga na te herenga riu.