Methyl 1,2,3,4-tetra-O-acetyl-BD-glucuronate Cas:7355-18-2 98%
Nama Putumōhio | XD90029 |
Ingoa Hua | methyl 1,2,3,4-tetra-O-acetyl-BD-glucuronate |
CAS | 7355-18-2 |
Tātai rāpoi | C15H20O11 |
Taumaha rāpoi | 376.31 |
Nga Taipitopito Rokiroki | 2-8 °C |
Waehere Rere Whakariterite | 29389090 |
Whakatakotoranga Hua
Te ahua | Ma ki te Tata ma te paura ki te karaihe |
Te whakamatautau | 98% |
Ko te Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucuronate kua whakamahia i roto i te rangahau ki te aromatawai i te hoahoa me te whakahiato o te wai-wairewa glucuronide derivatives o camptothecin mo te mate pukupuku prodrμg monotherapy me te antibody-directed enzyme prodrμg rongoā.I whakamahia ano i roto i te rangahau ki te tirotiro i te whakahiato me te mahi a nga heterocycles glycosylthio i roto i te matū warowaihā.
Te whakahiatotanga o nga hua o te waikawa pentopyranic
N4-Benzoylcytosine 1-(methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate) kua whiwhi me te hua o te 70% na te glycosylation o te trimethylsilyl derivative o N4-benzoylcytosine me te methyl 1,2 ,3,4-tetra-O-acetyl-β-D-glucopyranuronate i roto i te aroaro o te toru o nga rite o SnCl4 hei kaihoko whakamaarama.Ko te Cytosine 1-(β-D-glucopyranosiduronamide) (IV) - te amide o te waikawa pentopyranic - kua whakahiatohia i roto i nga hua tino ine e te ammonolysis o te nucleoside (I).