N-(2-Acetamide) waikawa iminodiacetic Cas: 26239-55-4 99% Te paura ma
| Nama Putumōhio | XD90194 |
| Ingoa Hua | ADA (N-(-2-Acetamido) waikawa iminodiacetic) |
| CAS | 26239-55-4 |
| Tātai rāpoi | C6H10N2O5 |
| Taumaha rāpoi | 190.15 |
| Nga Taipitopito Rokiroki | Ambient |
| Waehere Rere Whakariterite | 29241900 |
Whakatakotoranga Hua
| Fe | <5ppm |
| Pb | <5ppm |
| Ngaronga i te whakamaroke | <0.5% |
| Te pungarehu ngongo | <0.1% |
| Te ahua | Te paura ma |
| Ētahi atu Whakarewa | Karekau |
| Wā Whakarewa (9g i te 91ml 1M NaOH, Whakakorikori Autō) | <1min |
| A300 ( 9% i roto i te 1 M NaOH) | <0.08% |
| Te maha o nga pito ka kitea i roto i te ananga titration | E rua anake |
| Awhe pH e tautuhi ana i te Wehenga Whakamutunga Tuarua | 9.1 - 10.1 |
| Wairewa (9% i roto i te 1M NaOH) | Maama me te Taekore |
| Te ra hanga | |
| Wai KF | <1% |
| Whakamātautau (Titration) i runga i te tikanga maroke | >99.0% |
| Infrared | Ka tutuki |
Ko te nucleoside adenosine e mahi ana i runga i nga punaha nerve me te ngakau ma te A2A receptor (A2AR).Hei whakautu ki te taumata o te hāora i roto i nga kopa, ka whakatauhia te kukū o te plasma adenosine i roto i tana whakahiatotanga e te CD73 me tana whakahekenga e te adenosine deaminase (ADA).Ko te endopeptidase CD26 te mata-a-ira e whakahaere ana i te kukū o nga peptides vasoactive me te antioxidant, na reira ka whakahaere i te tuku hāora ki nga kopa me te whakautu ahotea oxidative.Ahakoa te nui o te whakahuatanga o te adenosine, CD73, ADA, A2AR, me te CD26 i roto i te whakautu ki te hypoxia he pai te tuhi, ko nga paanga o nga tikanga hyperoxic me te hyperbaric i runga i enei waahanga e tika ana kia whakaarohia ano.Ko nga kiore me tetahi raina pūtau Chem-3 murine e whakaatu ana i te A2AR i kitea ki te 0.21 pae O2, 0.79 pae N2 (nga tikanga whenua; normoxia);1 pae O2 (hyperoxia);2 pae O2 (hyperbaric hyperoxia);0.21 pae O2, 1.79 pae N2 (hyperbaria).Adenosine plasma concentration, CD73, ADA, A2AR expression, and CD26 activity were addressed in vivo, and cAMP production was addressed in cellulo.Mo nga ahuatanga i roto i te vivo, 1) ka whakahekehia e te hyperoxia te taumata plasma adenosine me te mahi CD26 mata o te pūtau T, engari i piki ake te whakaaturanga CD73 me te taumata ADA;2) ko te hyperbaric hyperoxia i kaha ki te whakanui i te ia;me te 3) ko te hyperbaria anake kaore he awe nui ki enei tawhā.I roto i te roro me te cellulo, 1) ka heke te hyperoxia ki te whakapuaki A2AR;2) ko te hyperbaric hyperoxia i whakanui i te ia;me te 3) ko te hyperbaria anake i whakaatu te kaha kaha.I kitea e matou he tauira rite mo te whakahiato A2AR mRNA i roto i te roro me te hanga cAMP i roto i nga ruma Chem-3.Na te taumata o te hāora teitei i whakaheke i te ara adenosinergic me te mahi CD26.Ko te Hyperbaria anake i pa ki te whakaaturanga A2AR me te hanga cAMP.Ka matapakihia me pehea e taea ai e enei momo mahi na te hyperoxygenation te whakaiti, na roto i te whakaheke toto, te tuku hāora ki nga kopa me te hanga o nga momo hāora tauhohenga.
