Hua

Ko te S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride, e mohiotia ana ko S-(+)-Clopidogrel, he pūhui rongoa me te tauira matū o C16H16ClNO2S·HCl He pärönaki chiral o te clopidogrel, he rongoa antiplatelet nui. Ko te whakamahinga tuatahi o S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride he kaha te whakauru i roto i te hanga o nga raau taero cardiovascular, ina koa ko nga kaihoko antiplatelet. Ka whakamahia e ia ona hua rongoa ma te aukati i te whakahiato pereti, te aukati i te hanganga o nga toto toto, me te whakaiti i te tupono o nga huihuinga cardiovascular. Ko te mahi nui ki te whakakorikori me te whakahiato o nga pereti ma te herenga korekore ki tenei kaiawhina, S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride ka aukati i te whakakorikori pereti me te aukati i te hanga. Ko tenei momo mahi ka waiho hei rongoa tino nui hei aukati i nga paheketanga thrombotic i roto i nga turoro e tino tupono ana, penei i te hunga e pa ana ki te mate o te mate coronary acute, te mate ischemic, te mate arai peripheral ranei.S-(+)-Methyl- (2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride i te nuinga o te wa ka tukuna ma te waha i te ahua o te papa, te kapene ranei.I muri i te horomitanga, ka puta he huringa metabolic i roto i te ate ki te whakaputa i tana metabolite kaha.Ka herea tenei metabolite kaha ki te kaiawhina P2Y12, ka whakapau i ona paanga antiplatelet mo te wa roa.I te nuinga o te wa ka tohua te puhui kotahi i ia ra, hei rongoa tuuturu, hei taapiri ranei me etahi atu rongoa antiplatelet, penei i te aspirini. -thienyl)amino] acetate hydrochloride me whakamahi noa i raro i te tohutohu a tetahi tohunga hauora, na te mea ka taea te whakamahi