Uridine-5′-diphosphoglucuronic acid trisodium tote CAS:63700-19-6 Te paura ma
| Nama Putumōhio | XD90382 |
| Ingoa Hua | Uridine-5'-diphosphoglucuronic acid trisodium tote |
| CAS | 63700-19-6 |
| Tātai rāpoi | C15H19N2O18P2Na3 |
| Taumaha rāpoi | 646.20 |
| Nga Taipitopito Rokiroki | < -4 °C |
Whakatakotoranga Hua
| Te whakamatautau | 99% |
| Te ahua | Te paura ma |
Ko te rangahau o naianei he tirotiro i te awe o te paitini o te irinotecan na te huringa koiora o te glucoaurantio-obtusin ki te aurantio-obtusin.Ko te whakahaerenga intraperitoneal (ip) o te 100 mg/kg aurantio-obtusin i tino piki ake te paitini o te irinotecan, engari ko te whakahaerenga ip o 100 mg/kg glucoaurantio-obtusin he iti te awe ki te paitini o te irinotecan.I tua atu, i whakamaramahia te tikanga ma te whakatau i te kaha o te aukati o te glucoaurantio-obtusin me te aurantio-obtusin ki te glucuronidation metabolism o SN-38 e kiia ana ko te hua tino kaha te kawenga mo te paitini o te irinotecan.Ko nga hua i whakaatu ko te aurantio-obtusin i whakaatu i te aukati whakataetae kaha ki te glucuronidation o SN-38, engari i kitea te kaha aukati o te glucoaurantio-obtusin ki te glucuronidation SN-38.I kitea e enei hua ko te huringa koiora o te glucoaurantio-obtusin ki te aurantio-obtusin i piki ake te paitini o te irinotecan na roto i te aukati i te SN-38 glucuronidation.
