![Bis[2-Hydroxyethyl] imino Tris-(Hydroxymethyl)-methane Cas: 6976-37-0 99% Whakaahua Whakaatu](http://cdn.globalso.com/xdbiochems/6976-37-0.jpg)
Bis[2-Hydroxyethyl] imino Tris-(Hydroxymethyl)-methane Cas: 6976-37-0 99%
| Nama Putumōhio | XD90111 |
| Ingoa Hua | BIS-TRIS (Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane) |
| CAS | 6976-37-0 |
| Tātai rāpoi | C8H20NO5 |
| Taumaha rāpoi | 210.2476 |
| Nga Taipitopito Rokiroki | Ambient |
| Waehere Rere Whakariterite | 2922190090 |
Whakatakotoranga Hua
| Nga konganuku taumaha | <10ppm |
| Te toenga i runga i te mura | <0.1% |
| Pka | 6.3-6.7 |
| Te ahua | Paura Tioata Ma |
| Wairewa (1M i H20) | Maama me te Whakaoti |
| pH (1M i H2O) | 9.0-11.0 |
| makuku (LOD) | 1.0% mōrahi. |
| Whakamātautau (Titration on dry basis) | 99.0% min. |
Buffer, whakamahia mo te kimi i te creatine-creatinase;whakamahia hoki mo te tiaki whai hua o te hemoglobin i roto i te whakamaroke-tio;catholyte, whakamahia i roto i te IEF/2-D gel electrophoresis.
Ko te tauwehe neurotrophic i ahu mai i te raina glial (GDNF) he aukati kaha mo te kai me te hokinga mai, a ko nga kiore GDNF heterozygous knockout e whakaatu ana i te whakanui ake i te aro ki te ewaro me te pau ake o te waihano i muri i te wa o te aukati i o raatau momo momo mohoao.I konei, i whakamatauria e maatau mehemea ka whakarereketia e te waihano te korero GDNF i roto i te rohe tegmental ventral (VTA; te waahi o te mahi a GDNF) me te / ranei te nucleus accumbens (NAc; te puna matua o te GDNF), a, ki te pera, whakatauhia te mahi o te take tipu endogenous. i roto i te whakaritenga o te kai ewaro.Ko te whakahaere punaha o te ethanol i piki ake te whakaaturanga GDNF me nga taumata pūmua i roto i te VTA, engari ehara i te NAc.I tua atu, i whakanuia nga taumata GDNF i muri i te inu waiwaro i roto i nga kiore i pau i te waihano i roto i te huarahi whiriwhiri-rua-pounamu mo te 1 wiki, engari kaua e 7 wiki.Ko te korenga i muri i nga wiki e 7 o te nui o te kai waipiro ka whakaheke i nga taumata GDNF, i te wa poto e inu ana i te waihano i muri mai i te korenga ka whakatika ake te korero GDNF.Ko te mea nui, ko te patototanga o te GDNF i roto i te VTA ma te whakamahi i te adenovirus e whakaatu ana i nga makawe poto RNA na te pikinga o te inu waihano e nga kiore ethanol-naïve, engari ehara i te kiore me te hitori o te nui o te kai ewaro.Ko enei hua e whakaatu ana i te wa tuatahi o nga wheako inu waihano, ka piki ake te GDNF i roto i te VTA me te tiaki i te whakawhanaketanga o te nui o te kai waipiro.Heoi, ka pakaru te urupare whakamarumaru o te mea tupu ki te waiwaro i muri i te roanga o te nui o te kai me te tangohanga o te waihano, ka puta te tohe, te nui o te kai ewaro.
