D-Valine Cas: 640-68-6 C5H11NO2
| Nama Putumōhio | XD90291 |
| Ingoa Hua | D-Valine |
| CAS | 640-68-6 |
| Tātai rāpoi | C5H11NO2 |
| Taumaha rāpoi | 117.14634 |
| Nga Taipitopito Rokiroki | Roa Temp |
| Waehere Rere Whakariterite | 29224995 |
Whakatakotoranga Hua
| Te whakamatautau | 99% |
| Te ahua | Te paura ma |
| Kiato | 1.2000 (whakatau tata) |
| Te rewa | >295 °C (whakaiti) (marama) |
| Kohuatanga | 213.6 °C i te 760 mmHg |
| Ira hiko | 83℃ |
| Taupū Refactive | -27 ° (C=8, 6mol/L HCl) |
| Wairewa | 56 g/L (20°C) |
| Te wairewa | 56 g/L (20ºC) |
| PSA | 63.32000 |
| RangitakiP | 0.75460 |
| Te hurihanga motuhake | -27.5 º (c=5, 5N HCl) |
| Mahi whatu | [α]23/D −32.0 ki te −24.0°, c = 8 i roto i te 6 M HCl |
Ko nga wahine whai mate antiphospholipid syndrome (APS) ka nui ake te mate o te mate haputanga (RPL) me te preeclampsia.Ko nga antiphospholipid antibodies (aPL) ka huri tika i te mahi trophoblast.Ko te maimoatanga me te heparin molecular weight heparin (LMWH) ka whakaiti i te tupono o te RPL engari kaua ko te preeclampsia.I tua atu, ka whakaihiihi a LMWH i te tuku trophoblast sFlt-1, he take anti-angiogenic e pa ana ki te preeclampsia.I te mea ko te ngoikoretanga o te huaora D e hono ana ki te APS me te preeclampsia, i rapu tenei rangahau ki te whakatau i te paanga o te huaora D ki te mahi trophoblast i roto i te whakatakotoranga o te aPL me te LMWH. Ko te raina o te trophoblast trophoblast tuatahi o te tangata (HTR8) me nga ahurea trophoblast tuatahi i tukinotia ranei kaore he aPL i te aroaro me te kore o te huaora D, LMWH, e rua ranei.Trophoblast secretion o cytokines inflammatory me te angiogenic āhuatanga i ine e ELISA.Vitamin D anake ranei i roto i te huinga ki LMWH attenuated te aPL-induced trophoblast inflammatory whakautu i roto i te HTR8 pūtau me ahurea tuatahi.Ahakoa kaore he paanga o te huaora D ki te whakarereketanga aPL-takawaenga o nga mea angiogenic i roto i te trophoblast tuatahi, ka tino aukatihia e te LMWH te tuku sFlt-1. Ko te LMWH me te huaora D ka nui ake te painga atu i te rongoa a te kaihoko kotahi ma te aukati i te aPL - te mumura o te trophoblast me te whakahuri i te sFlt-1 i te LMWH.
