ITP, inosine 5′-triphosphate trisodium tote
| Nama Putumōhio | XD90558 |
| Ingoa Hua | ITP, inosine 5'-triphosphate trisodium tote |
| CAS | 35908-31-7 |
| Tātai rāpoi | C10H12N4Na3O14P3 |
| Taumaha rāpoi | 574.111 |
| Nga Taipitopito Rokiroki | Ambient |
| Waehere Rere Whakariterite | 29349990 |
Whakatakotoranga Hua
| Te ahua | Te paura ma |
| Te whakamatautau | 99% |
I whakamahia te hiranga infrared ki te mapi i nga taunekeneke substrate-protein: ko nga huringa o te sarcoplasmic reticulum Ca(2+)-ATPase i runga i te here nucleotide me te ATPase phosphorylation i aroturukitia ma te whakamahi i te substrate ATP me ATP analogues (2'-deoxy-ATP, 3 '-deoxy-ATP, me te inosine 5'-triphosphate), i whakarereketia i nga roopu mahi motuhake o te taputapu.Ko nga whakarereketanga ki te 2'-OH, te 3'-OH, me te roopu amino o te adenine ka whakaiti i te nui o te whakarereketanga o te ATPase, me nga paanga kaha e kitea ana mo nga mea e rua.Ka whakaatu tenei i te kaha o te hanganga o te matatini nucleotide-ATPase ki nga taunekeneke takitahi i waenga i te nucleotide me te ATPase.Ko nga roopu katoa i akohia he mea nui mo te here me te taunekeneke o tetahi roopu roopu me te ATPase e whakawhirinaki ana ki nga taunekeneke o etahi atu roopu ligand.Ko te Phosphorylation o te ATPase i kitea mo te ITP me te 2'-deoxy-ATP, engari mo te 3'-deoxy-ATP.Karekau he hononga tika i waenga i te nui o te whakarereketanga i runga i te herenga nucleotide me te tere o te phosphorylation e whakaatu ana ko te whānuitanga katoa o te huringa conformational i whakaawehia e te ATP ehara i te whakahau mo te phosphorylation.I kitea mo te matatini nucleotide-ATPase, ko te hangahanga o te ATPase takawaenga tuatahi E1PCa(2) ka whakawhirinaki ano ki te nucleotide, e tohu ana he iti ake te ahua o nga ahua o te ATPase i te ahua o mua.
